《'十二五'普通高校教育本科規劃教材:全新版21世紀大學英語練習冊2》共8個單元。每單元均由5部分組成：第一部分為聽力，第二部分為詞匯和結構，第三部分為翻譯，第四部分為閱讀，第五部分為寫作。每單元使用的材料和《全新版21世紀大學英語讀寫教程》教材各單元主題一致。
《'十二五'普通高校教育本科規劃教材:全新版21世紀大學英語練習冊2》根據《大學英語課程教學要求》中有關教學內容和課程體系改革的精神，與時俱進，加大了“聽、說”訓練的力度，將視聽說題材與課文主題保持一致，把聽、說、讀、寫的技能訓練有機地結合起來，使學生的聽、說訓練貫穿于整個課程教學的始終。
Unit 1 Bonds of Friendship
Part Ⅰ Listening
Part Ⅱ Vocabulary and Structure
Part Ⅲ Translating
Part Ⅳ Reading
Part Ⅴ Writing
Unit 2 Road to Success
Part Ⅰ Listening
Part Ⅱ Vocabulary and Structure
Part Ⅲ Translating
Part Ⅳ Reading
Part Ⅴ Writing
Unit 3 Being True to One's Self
Part Ⅰ Listening
Part Ⅱ Vocabulary and Structure
Part Ⅲ Translating
Part Ⅳ Reading
Part Ⅴ Writing
Unit 4 Cultural Values
Part Ⅰ Listening
Part Ⅱ Vocabulary and Structure
Part Ⅲ Translating
Part Ⅳ Reading
Part Ⅴ Writing
Unit 5 A Piece of Advice
Part Ⅰ Listening
Part Ⅱ Vocabulary and Structure
Part Ⅲ Translating
Part Ⅳ Reading
Part Ⅴ Writing
Unit 6 Future World
Part Ⅰ Listening
Part Ⅱ Vocabulary and Structure
Part Ⅲ Translating
Part Ⅳ Reading
Part Ⅴ Writing
Unit 7 Non-Human Earthlings
Part Ⅰ Listening
Part Ⅱ Vocabulary and Structure
Part Ⅲ Translating
Part Ⅳ Reading
Part Ⅴ Writing
Unit 8 New Technology
Part Ⅰ Listening
Part Ⅱ Vocabulary and Structure
Part Ⅲ Translating
Part Ⅳ Reading
Part Ⅴ Writing
Key
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