本書保持了前八版的編寫特色:注重基礎(chǔ)知識,概念清晰準(zhǔn)確,探討解決專業(yè)問題,師生易學(xué)易教。第九版內(nèi)容拓展到基因組、生物信息、蛋白質(zhì)組及相關(guān)前沿領(lǐng)域。該書在亞馬遜專業(yè)教材銷售排行榜長期名列前茅,被許多北美、歐洲高校教學(xué)選用。
第九版內(nèi)容主要包括:遺傳學(xué)概況,有絲分裂和減數(shù)分裂,孟德爾遺傳學(xué),孟德爾比率,真核生物染色體圖譜,細(xì)菌和噬菌體的遺傳分析,性別決定和性染色體,染色體突變:染色體數(shù)量和分布,核外遺傳,dna結(jié)構(gòu)與分析,dna復(fù)制與重組,染色體dna的組織,重組dna技術(shù)和基因克隆,遺傳密碼和轉(zhuǎn)錄,翻譯,基因突變和dna修復(fù),原核生物基因表達(dá),真核生物基因表達(dá)調(diào)控,模式生物的發(fā)育遺傳學(xué),癌癥和細(xì)胞周期調(diào)控,基因組學(xué),蛋白質(zhì)組學(xué),生物信息學(xué),基因組動力學(xué):轉(zhuǎn)座子,免疫遺傳學(xué),真核病毒,基因組分析——基因功能,基因工程的應(yīng)用及生物倫理剖析,數(shù)量遺傳學(xué)和多因子性狀,行為遺傳學(xué),群體遺傳學(xué),進(jìn)化遺傳學(xué),保護(hù)遺傳學(xué)。
本書適合生命科學(xué)相關(guān)專業(yè)教學(xué)選用,也可供從業(yè)人員參考使用。
part one genes,chromosomes,andheredity
1 introduction to genetics 1
2 mitosis and meiosis18
3 mendelian genetics42
4 extensions of mendelian genetics70
5 chromosome mapping in eukaryotes 105
6 genetic analysis and mapping in bacteria andbacteriophages143
7 sex determination and sex chromosomes 173
8 chromosome mutations: variation in chromosome number andarrangement198
9 extranuclear inheritance227
part two dna: structure replication, and variation
10 dna structure and analysis245
11 dna replication and recombination278
12 dna organization in chromosomes302
13 recombinant dna technology and gene cloning322
part three gene expression,regulationand development
14 the genetic code and transcription352
15 translation and proteins381
16 gene mutation and dna repair410
17 regulation of gene expression in prokaryotes435
18 regulation of gene expression in eukaryotes457
19 developmental genetics of model organisms484
20 cancer and regulation of the cell cycle511
part four genomics
21 genomics, bioinformatics, and proteomics531
22 genome dynamics: transposons, immunogenetics, and eukaryoticviruses574
23 genomic analysis——dissection of gene function605
24 applications and ethics of genetic engineering andbiotechnology633
part five genetics of organisms and population
25 quantitative genetics and multifactorial traits668
26 genetics and behavior688
27 population genetics710
28 evolutionary genetics737
29 conservation genetics 762
appendix a glossarya-1
appendix b answers to selected problemsa-18
appendix c selected readingsa-57
creditsc-1
index i-1